Safety and Outcomes of Tenecteplase in Moderate and Severe Ischemic Stroke
                    
                        
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                    چکیده
منابع مشابه
Hemicraniectomy and moderate hypothermia in patients with severe ischemic stroke.
BACKGROUND AND PURPOSE We compared the clinical course of 36 consecutive patients with severe acute ischemic stroke (more than two thirds of the middle cerebral artery territory) treated with hemicraniectomy (CE; n=17) or moderate hypothermia (MH; n=19) in terms of intracranial pressure control, mortality, and specific treatment parameters. METHODS Over a period of 18 months, patients with se...
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A pilot dose-escalation safety study of tenecteplase in acute ischemic stroke.
BACKGROUND AND PURPOSE Recombinant tissue-type plasminogen activator (rtPA) is the only approved treatment in acute ischemic stroke. However, intracerebral hemorrhage (ICH) occurs in 6.4% of patients treated with rtPA and limits its use. Tenecteplase (TNK) is a modified form of rtPA, with longer half-life and greater fibrin specificity. Patients after myocardial infarction had fewer systemic he...
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ژورنال
عنوان ژورنال: Stroke
سال: 2019
ISSN: 0039-2499,1524-4628
DOI: 10.1161/strokeaha.119.025041